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IC/BPS‐associated alterations of M2 and M3 muscarinic acetylcholine receptor trafficking in human detrusor

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To explore caveolae‐ and clathrin‐mediated internalization of muscarinic M2 and M3 receptors, recycling and degradation in formalin‐fixed paraffin‐embedded detrusor sections; to study alterations possibly involved in the pathophysiology of the… Click to show full abstract

To explore caveolae‐ and clathrin‐mediated internalization of muscarinic M2 and M3 receptors, recycling and degradation in formalin‐fixed paraffin‐embedded detrusor sections; to study alterations possibly involved in the pathophysiology of the bladder functional disorder, interstitial cystitis/bladder pain syndrome (IC/BPS).

Keywords: detrusor; alterations muscarinic; muscarinic acetylcholine; bps associated; associated alterations; acetylcholine receptor

Journal Title: Neurourology and Urodynamics
Year Published: 2019

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