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Functional MRI in patients with detrusor sphincter dyssynergia: Is the neural circuit affected?

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In recent years, the human brain‐bladder control network has been visualized in different functional magnetic resonance imaging (fMRI) studies. The role of the brainstem and suprapontine regions has been elucidated.… Click to show full abstract

In recent years, the human brain‐bladder control network has been visualized in different functional magnetic resonance imaging (fMRI) studies. The role of the brainstem and suprapontine regions has been elucidated. Especially the pontine region and the periaqueductal gray, as the central structures of the micturition circuit, were demonstrated. Detrusor sphincter dyssynergia (DSD) is a common problem in patients with neurological diseases. Residual urine and consecutive urinary tract infections with the risk of kidney damage remain a problem. In the present study, we used fMRI of the brain to compare the activation sites of patients with DSD with those of our previously published healthy controls with special emphasis on the brainstem region.

Keywords: functional mri; sphincter dyssynergia; mri patients; patients detrusor; circuit; detrusor sphincter

Journal Title: Neurourology and Urodynamics
Year Published: 2019

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