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A novel waterjet technology for transurethral cystoscopic injection of viable cells in the urethral sphincter complex

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In a recent preclinical study, we noticed that injection of cells in the urethral sphincter by needle through a cystoscope under visual control frequently yielded in misplacement or loss of… Click to show full abstract

In a recent preclinical study, we noticed that injection of cells in the urethral sphincter by needle through a cystoscope under visual control frequently yielded in misplacement or loss of cells. We, therefore, investigated if a needle‐free waterjet device delivers viable cells under defined settings, including injection volume and pressure, fluid velocity and transportation media, precisely through the urothelium and connective tissue close to the sphincter muscle without full penetration of the sphincter apparatus.

Keywords: cells urethral; sphincter; urethral sphincter; viable cells; injection; waterjet

Journal Title: Neurourology and Urodynamics
Year Published: 2019

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