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TIMP‐2 as a noninvasive urinary marker for predicting neurogenic bladder in patients under follow‐up for spina bifida

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Neurogenic bladder (NB) post‐meningomyelocele (MMC) repair is a major challenge and needs lifelong follow‐up. Many cytokines have been implicated in the pathogenesis of NB. To avoid repeated urodynamic studies (UDS)… Click to show full abstract

Neurogenic bladder (NB) post‐meningomyelocele (MMC) repair is a major challenge and needs lifelong follow‐up. Many cytokines have been implicated in the pathogenesis of NB. To avoid repeated urodynamic studies (UDS) and renal scans, we studied urinary tissue inhibitors of metalloproteinases‐2 (TIMP‐2) levels and correlated with urodynamic profiles to establish their efficacy.

Keywords: neurogenic bladder; bladder; marker predicting; noninvasive urinary; urinary marker; timp noninvasive

Journal Title: Neurourology and Urodynamics
Year Published: 2020

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