Photo by kellysikkema from unsplash
Bladder outlet obstruction (BOO) is a common problem that can affect bladder structure and function. Currently, there is no effective drugs available to prevent BOO‐induced remodeling. Previous reports have demonstrated… Click to show full abstract
Bladder outlet obstruction (BOO) is a common problem that can affect bladder structure and function. Currently, there is no effective drugs available to prevent BOO‐induced remodeling. Previous reports have demonstrated that the pathogenesis of BOO is associated with macrophage infiltration and polarization, which is physiologically dependent on colony‐stimulating factor 1 receptor (CSF‐1R) activation. Here we utilized a highly selective CSF‐1R inhibitor, GW2580, to determine its preventive effects on BOO‐induced remodeling.
Journal Title: Neurourology and Urodynamics
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!