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Changes in median eminence of fatty acid–binding protein 3 in a mouse model of pain

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Fatty acid–binding protein (FABP) regulates polyunsaturated fatty acid (PUFA) intracellular trafficking and signal transduction. Our previous studies demonstrated that the alteration of PUFA in the hypothalamus is involved in pain… Click to show full abstract

Fatty acid–binding protein (FABP) regulates polyunsaturated fatty acid (PUFA) intracellular trafficking and signal transduction. Our previous studies demonstrated that the alteration of PUFA in the hypothalamus is involved in pain process. However, how FABP subtypes change during pain remain unclear. Here, we examined the expression changes and localization in the hypothalamic FABP subtype in postoperative pain model mice.

Keywords: binding protein; fatty acid; pain; acid binding

Journal Title: Neuropsychopharmacology Reports
Year Published: 2022

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