LAUSR

OBJECTIVE The objective of this study is to assess the impact of a history of metabolic and bariatric surgery (MBS) on the clinical outcomes in patients with type 2 diabetes (T2D) and severe obesity hospitalized for COVID-19. METHODS Post-hoc analysis from the nationwide observational CORONADO study: patients with T2D and history of MBS were matched with patients without MBS for age, sex and body mass index (BMI) either at the time of MBS or on admission for COVID-19. The composite primary outcome (CPO) combined invasive mechanical ventilation and/or death within 7 and 28 days following admission. RESULTS Out of 2 398 CORONADO participants, 20 had history of MBS. When matching for BMI at the time of MBS and after adjustment on diabetes duration, the CPO occurred less frequently within 7 days (3 vs 17 events, OR: 0.15 [0.01-0.94], P=0.03) and 28 days (3 vs 19 events, OR: 0.11 (0.01-0.71), P=0.02) in patients with MBS (n=16) vs controls (n=44). There was no difference in CPO rate between patients with MBS and controls when matching for BMI on admission. CONCLUSIONS These data are reassuring regarding COVID-19 prognosis in patients with diabetes with history of MBS compared to those without MBS.