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Monoacylglycerol O‐acyltransferase 1 lowers adipocyte differentiation capacity in vitro but does not affect adiposity in mice

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Monoacylglycerol O‐acyltransferase 1 (Mogat1), a lipogenic enzyme that converts monoacylglycerol to diacylglycerol, is highly expressed in adipocytes and may regulate lipolysis by re‐esterifying fatty acids released during times when lipolytic… Click to show full abstract

Monoacylglycerol O‐acyltransferase 1 (Mogat1), a lipogenic enzyme that converts monoacylglycerol to diacylglycerol, is highly expressed in adipocytes and may regulate lipolysis by re‐esterifying fatty acids released during times when lipolytic rates are low. However, the role of Mogat1 in regulating adipocyte fat storage during differentiation and diet‐induced obesity is relatively understudied.

Keywords: acyltransferase lowers; monoacylglycerol acyltransferase; lowers adipocyte; differentiation; monoacylglycerol

Journal Title: Obesity
Year Published: 2022

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