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An Electrochemical Way to Generate Amphiphiles from Hydrazones for the Synthesis of 1,2,4‐Triazole Scaffold Cyclic Compounds

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Abstract An electro‐oxidative cyclization pathway in which hydrazones are selected as starting materials to generate amphiphiles by reacting with benzylamines and benzamides was reported. This strategy successfully prepared a series… Click to show full abstract

Abstract An electro‐oxidative cyclization pathway in which hydrazones are selected as starting materials to generate amphiphiles by reacting with benzylamines and benzamides was reported. This strategy successfully prepared a series of 1,2,4‐triazoles in satisfactory yields. Moreover, the use of cheap stainless steel as the anode, the feasibility to conduct the transformation as a one‐pot reaction and the proof that scaling‐up these reactions is possible make this transformation attractive for potential application in industry.

Keywords: hydrazones synthesis; way generate; electrochemical way; generate amphiphiles; synthesis triazole; amphiphiles hydrazones

Journal Title: ChemistryOpen
Year Published: 2022

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