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PGT‐A: The biology and hidden failures of randomized control trials

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Preimplantation Genetic Testing ‐ Aneuploidy (PGT‐A) for embryo selection has undergone significant advancements in the last 2 decades and yet many studies still fail to demonstrate any clinical benefits over… Click to show full abstract

Preimplantation Genetic Testing ‐ Aneuploidy (PGT‐A) for embryo selection has undergone significant advancements in the last 2 decades and yet many studies still fail to demonstrate any clinical benefits over traditional embryo morphology selection (Mo‐S). To understand this conundrum, we performed a multi‐center clinical study of PGT‐A patients, where Mo‐S and euploid selection (Eu‐S) outcomes were directly compared.

Keywords: failures randomized; randomized control; biology hidden; pgt biology; hidden failures; biology

Journal Title: Prenatal Diagnosis
Year Published: 2022

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