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Isolation of single circulating trophoblasts from maternal circulation for noninvasive fetal copy number variant profiling

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To develop a multi‐step workflow for the isolation of circulating extravillous trophoblasts (cEVTs) by describing the key steps enabling a semi‐automated process, including a proprietary algorithm for fetal cell origin… Click to show full abstract

To develop a multi‐step workflow for the isolation of circulating extravillous trophoblasts (cEVTs) by describing the key steps enabling a semi‐automated process, including a proprietary algorithm for fetal cell origin genetic confirmation and copy number variant (CNV) detection.

Keywords: isolation single; number variant; copy number

Journal Title: Prenatal Diagnosis
Year Published: 2022

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