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Immeasurable time bias due to hospitalization in medico‐administrative databases: which impact for pharmacoepidemiological studies?

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Drugs administered to hospitalized patients are not available within almost all health insurance databases. However, this unobservable exposure time bias is very rarely taken into account in pharmacoepidemiology. The objective… Click to show full abstract

Drugs administered to hospitalized patients are not available within almost all health insurance databases. However, this unobservable exposure time bias is very rarely taken into account in pharmacoepidemiology. The objective was to model unobservable periods due to hospitalization and to assess their impact on risk estimates in the context of the association between benzodiazepines and mortality.

Keywords: time bias; bias due; due hospitalization; immeasurable time

Journal Title: Pharmacoepidemiology and Drug Safety
Year Published: 2017

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