Case reports and pharmacokinetic studies have suggested that concomitant use of low‐dose methotrexate and nonsteroidal anti‐inflammatory drugs (NSAIDs) may be associated with increased risk of methotrexate toxicity. This study aimed… Click to show full abstract
Case reports and pharmacokinetic studies have suggested that concomitant use of low‐dose methotrexate and nonsteroidal anti‐inflammatory drugs (NSAIDs) may be associated with increased risk of methotrexate toxicity. This study aimed to investigate the risk of serious adverse events associated with concomitant use of low‐dose methotrexate and NSAIDs, compared with use of methotrexate alone, among patients with rheumatoid arthritis.
               
Click one of the above tabs to view related content.