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Early into COVID, human challenge trials were considered, but usually as alternatives to conventional randomized controlled trials. Instead, assessment of authorized COVID vaccines, of further COVID vaccines, and of vaccines… Click to show full abstract
Early into COVID, human challenge trials were considered, but usually as alternatives to conventional randomized controlled trials. Instead, assessment of authorized COVID vaccines, of further COVID vaccines, and of vaccines against future pandemics should combine both designs, in five different ways, including a wholly novel one that we elaborate, Viz., combining data from both designs to answer a single question.
Keywords:
testing combining;
conventional challenge;
combining conventional;
pandemic vaccine;
vaccine testing;
challenge
Journal Title: Pharmacoepidemiology and Drug Safety
Year Published: 2022
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Journal Title: Pharmacoepidemiology and Drug Safety
Year Published: 2022
Link to full text (if available)
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recommendations!