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The acute effects of azithromycin use on cardiovascular mortality as compared with amoxicillin–clavulanate in US Veterans

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Azithromycin is a common first‐line antibiotic for respiratory infection; however, there is conflicting evidence regarding risk of cardiovascular death. We assessed cardiovascular and noncardiovascular mortality associated with azithromycin versus amoxicillin–clavulanate… Click to show full abstract

Azithromycin is a common first‐line antibiotic for respiratory infection; however, there is conflicting evidence regarding risk of cardiovascular death. We assessed cardiovascular and noncardiovascular mortality associated with azithromycin versus amoxicillin–clavulanate among US Veterans treated for nonear–nose–throat respiratory infection (“respiratory”) or ear–nose–throat infection indication.

Keywords: acute effects; mortality; effects azithromycin; amoxicillin clavulanate; azithromycin use

Journal Title: Pharmacoepidemiology and Drug Safety
Year Published: 2022

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