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The Effect of Isoniazid for Tuberculosis Prevention on Pregnancy Risk Among Women Living With HIV on Antiretroviral Treatment and Progestin‐Based Hormonal Contraception

Concomitant use of antiretroviral therapy (ART), hormonal contraception, and isonicotinic acid hydrazide (isoniazid) for tuberculosis prevention is common among women of reproductive age who are living with HIV in sub‐Saharan… Click to show full abstract

Concomitant use of antiretroviral therapy (ART), hormonal contraception, and isonicotinic acid hydrazide (isoniazid) for tuberculosis prevention is common among women of reproductive age who are living with HIV in sub‐Saharan Africa. We estimated the effect of isoniazid on 6‐month pregnancy risk among Malawian women living with HIV in the Family Planning and Antiretroviral Therapy (FP‐ART) prospective cohort study, overall and among subgroups defined by ART regimen type and hormonal contraceptive method.

Keywords: isoniazid tuberculosis; hormonal contraception; living hiv; tuberculosis prevention; among women; effect isoniazid

Journal Title: Pharmacoepidemiology and Drug Safety
Year Published: 2025

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