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Carpino's protecting groups, beyond the Boc and the Fmoc

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Peptide synthesis is often defined as “the suitable combination of protecting groups and coupling reagents.” This sentence can also be used to define the scientific career of Professor Louis A.… Click to show full abstract

Peptide synthesis is often defined as “the suitable combination of protecting groups and coupling reagents.” This sentence can also be used to define the scientific career of Professor Louis A. Carpino, who revolutionized peptide synthesis through the development of new paradigms in both protecting groups and coupling reagents. This review addresses the contributions of Professor Carpino to the former, not from a historical perspective but rather with the intention of revisiting his work as inspiration for the development of new chemistries.

Keywords: groups beyond; boc fmoc; beyond boc; carpino protecting; protecting groups; carpino

Journal Title: Peptide Science
Year Published: 2020

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