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The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) potentiator ivacaftor (Kalydeco®) improves clinical outcome in G551D cystic fibrosis (CF) patients. Here, we have investigated whether ivacaftor has a clinical impact on… Click to show full abstract
The Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) potentiator ivacaftor (Kalydeco®) improves clinical outcome in G551D cystic fibrosis (CF) patients. Here, we have investigated whether ivacaftor has a clinical impact on non‐G551D gating mutations and function of circulating leukocytes as well.
Keywords:
ivacaftor;
cystic fibrosis;
fibrosis;
cftr dependent;
dependent chloride
Journal Title: Pediatric Pulmonology
Year Published: 2017
Link to full text (if available)
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Journal Title: Pediatric Pulmonology
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!