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Tracheal aspirate VEGF and sphingolipid metabolites in the preterm infant with later development of bronchopulmonary dysplasia

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Vascular endothelial growth factor (VEGF) and sphingolipid metabolites, sphingosine 1‐phosphate (S1P), and ceramides are important to lung development and repair. We hypothesized specific sphingolipid and VEGF alterations would be associated… Click to show full abstract

Vascular endothelial growth factor (VEGF) and sphingolipid metabolites, sphingosine 1‐phosphate (S1P), and ceramides are important to lung development and repair. We hypothesized specific sphingolipid and VEGF alterations would be associated with BPD development and aimed to investigate the early tracheal aspirate (TA) VEGF and S1P relationship with later diagnosis of preterm infant bronchopulmonary dysplasia, BPD.

Keywords: vegf; vegf sphingolipid; sphingolipid metabolites; aspirate vegf; tracheal aspirate; development

Journal Title: Pediatric Pulmonology
Year Published: 2018

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