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Scond is a multiple breath washout (MBW) index that measures convection‐dependent ventilation inhomogeneity (CDI) arising within conductive airways, but the calculation method is unreliable in subjects with advanced cystic fibrosis… Click to show full abstract
Scond is a multiple breath washout (MBW) index that measures convection‐dependent ventilation inhomogeneity (CDI) arising within conductive airways, but the calculation method is unreliable in subjects with advanced cystic fibrosis (CF) lung disease. A new CDI index, Scond*, has been proposed for use in adults with CF and moderate to severe ventilation inhomogeneity. We aimed to evaluate the most appropriate CDI index in children and adolescents with CF and various degrees of inhomogeneity, and from that the most appropriate diffusion‐convection‐interaction index (Sacin or Sacin*).
Journal Title: Pediatric Pulmonology
Year Published: 2020
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