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Dead space washout by intentional leakage flow during conventional ventilation of premature infants—an experimental study

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Invasive mechanical ventilation poses a strong risk factor for the development of chronic lung disease in preterm infants. A reduction of the dead space as part of the total breathing… Click to show full abstract

Invasive mechanical ventilation poses a strong risk factor for the development of chronic lung disease in preterm infants. A reduction of the dead space as part of the total breathing volume would reduce the ventilation effort and thereby lower the risk of ventilator‐induced lung injuries. In this experimental study, we compared the efficacy of mechanical dead space washout via uncontrolled and controlled leakage flow in their ability to eliminate CO2 during conventional ventilation in preterm infants.

Keywords: space washout; dead space; leakage flow; ventilation; experimental study

Journal Title: Pediatric Pulmonology
Year Published: 2022

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