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Pulmonary exacerbations, airway pathogens, and long‐term course of lung clearance index in children and young adults with cystic fibrosis

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Pulmonary exacerbations (PEx), pathogens colonizing the respiratory tract, and patients' age are associated with progressive worsening of lung function among patients with cystic fibrosis (CF). However, the effect of these… Click to show full abstract

Pulmonary exacerbations (PEx), pathogens colonizing the respiratory tract, and patients' age are associated with progressive worsening of lung function among patients with cystic fibrosis (CF). However, the effect of these factors on longitudinal changes of Lung Clearance Index (LCI) remains unclear.

Keywords: cystic fibrosis; lung clearance; clearance index; pulmonary exacerbations

Journal Title: Pediatric Pulmonology
Year Published: 2022

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