LAUSR

The development of agrochemical products faces many scientific challenges. After selection of an agrochemical candidate its properties will have to be optimized to guarantee best bioavailability and stability under many different conditions in various formulation types. These challenges are influenced by the solid-state properties of the active ingredient and this makes the selection of an optimized solid-state form of modern agrochemicals at early development stages very valuable. The increasing awareness of the solid state of agrochemicals is reflected in the importance of polymorphism patent applications, which may enhance the risk of litigations. This review aims to present strategies for the solid-form selection process of agrochemical development candidates. It introduces the different techniques for crystallization and analytics and demonstrates the influence of the solid state on different formulation types. This article is protected by copyright. All rights reserved.