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Impact of metabolic disorders on prostate cancer growth: Androgen and insulin resistance perspectives

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A high prevalence of cancers in metabolic disorders, like metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM), recently has been noted, including prostate cancer (PC), which is androgen‐sensitive. However,… Click to show full abstract

A high prevalence of cancers in metabolic disorders, like metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM), recently has been noted, including prostate cancer (PC), which is androgen‐sensitive. However, the pathological relationship among testosterone and insulin and insulin‐like growth factor (IGF)‐1 signaling in relation to MetS and T2DM with PC remains unclear.

Keywords: insulin; impact metabolic; prostate cancer; metabolic disorders; growth

Journal Title: Reproductive Medicine and Biology
Year Published: 2017

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