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Pre‐implantation genetic testing (PGT) has been performed worldwide since it was first used by Handyside et al in the United Kingdom to sex embryos in 1990. Until about 2010, cleavage… Click to show full abstract
Pre‐implantation genetic testing (PGT) has been performed worldwide since it was first used by Handyside et al in the United Kingdom to sex embryos in 1990. Until about 2010, cleavage stage embryo biopsy and fluorescent in situ hybridization (FISH) were mainstream; however, in 2012, blastocyst biopsy (trophectoderm; TE biopsy) became mainstream. In addition, array comparative genomic hybridization (aCGH) was used for analysis and further evolved to next‐generation sequencing (NGS), which is used worldwide.
Keywords:
genetic testing;
pre implantation;
testing past;
implantation genetic;
past present
Journal Title: Reproductive Medicine and Biology
Year Published: 2021
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Journal Title: Reproductive Medicine and Biology
Year Published: 2021
Link to full text (if available)
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recommendations!