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A gene network of uterine luminal epithelium organizes mouse blastocyst implantation

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The receptive endometrium is critical for blastocyst implantation. In mice, after blastocysts enter the uterine cavities on day 4 of pregnancy (day 1 = vaginal plug), blastocyst attachment is completed… Click to show full abstract

The receptive endometrium is critical for blastocyst implantation. In mice, after blastocysts enter the uterine cavities on day 4 of pregnancy (day 1 = vaginal plug), blastocyst attachment is completed within 24 h, accompanied by dynamic interactions between the uterine luminal epithelium and the blastocysts. Any failures in this process compromise subsequent pregnancy outcomes. Here, we performed comprehensive analyses of gene expression at the luminal epithelium in the periā€implantation period.

Keywords: blastocyst; luminal epithelium; uterine luminal; blastocyst implantation

Journal Title: Reproductive Medicine and Biology
Year Published: 2022

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