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Microstructure and biological activity of silicon‐doped composite coatings fabricated by micro‐arc oxidation on magnesium alloy

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Among biomaterials, the mechanical properties of magnesium and its alloys are closest to those of human bone tissue, making these ideal materials for bone tissue repair and replacement. In order… Click to show full abstract

Among biomaterials, the mechanical properties of magnesium and its alloys are closest to those of human bone tissue, making these ideal materials for bone tissue repair and replacement. In order to further improve the biocompatibility and biological activity of the magnesium alloy AZ91D, micro‐arc oxidation with a constant‐current power supply mode was employed in this study in a silicate electrolyte solution. The resultant coating surface had a porous structure, and silicon was evenly distributed in it. Further, the results of in vitro experimental studies showed that the silicon‐doped magnesium coating on the surface of the magnesium alloys has no obvious cytotoxicity, and it can induce the proliferation of osteoblasts and promote actin stretching. In addition, it has good biological activity and biocompatibility. Thus, the novel method developed in this study improves the potential for clinical applications of magnesium alloys.

Keywords: biological activity; micro arc; magnesium; silicon; magnesium alloy

Journal Title: Surface and Interface Analysis
Year Published: 2020

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