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High-dimensional single-index models with censored responses.

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In this article, we study the estimation of high-dimensional single index models when the response variable is censored. We hybrid the estimation methods for high-dimensional single-index models (but without censorship)… Click to show full abstract

In this article, we study the estimation of high-dimensional single index models when the response variable is censored. We hybrid the estimation methods for high-dimensional single-index models (but without censorship) and univariate nonparametric models with randomly censored responses to estimate the index parameters and the link function and apply the proposed methods to analyze a genomic dataset from a study of diffuse large B-cell lymphoma. We evaluate the finite sample performance of the proposed procedures via simulation studies and establish large sample theories for the proposed estimators of the index parameter and the nonparametric link function under certain regularity conditions.

Keywords: high dimensional; index; censored responses; single index; index models; dimensional single

Journal Title: Statistics in medicine
Year Published: 2020

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