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Lamotrigine (LTG) is a broad‐spectrum antiepileptic drug that is widely used in clinic. However, the effect of LTG on cognition and neurodegeneration during epilepsy treatment remains controversial. In this study,… Click to show full abstract
Lamotrigine (LTG) is a broad‐spectrum antiepileptic drug that is widely used in clinic. However, the effect of LTG on cognition and neurodegeneration during epilepsy treatment remains controversial. In this study, we compared the cognitive effects of LTG and sodium valproate in pentylenetetrazole (PTZ)‐kindled animal model, and the dose dependency was tested for LTG.
Keywords:
epilepsy;
animal model;
effect;
kindled animal;
pentylenetetrazole;
lamotrigine
Journal Title: Synapse
Year Published: 2017
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Journal Title: Synapse
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!