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Development of lacrimal gland spheroids for lacrimal gland tissue regeneration

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Severe dry eye syndrome resulting from lacrimal gland (LG) dysfunction can cause blindness, yet treatments remain palliative. In vitro reconstruction of LG tissue could provide a curative treatment. We aimed… Click to show full abstract

Severe dry eye syndrome resulting from lacrimal gland (LG) dysfunction can cause blindness, yet treatments remain palliative. In vitro reconstruction of LG tissue could provide a curative treatment. We aimed to combine epithelial cells with endothelial cells and mesenchymal stem cells (MSCs) to form a 3D functional unit.

Keywords: tissue; spheroids lacrimal; lacrimal gland; development lacrimal; gland spheroids

Journal Title: Journal of Tissue Engineering and Regenerative Medicine
Year Published: 2018

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