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Fundamentals of the Dynorphins/Kappa Opioid Receptor System: From Distribution to Signaling and Function.

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This chapter provides a general introduction to the dynorphins (DYNs)/kappa opioid receptor (KOR) system, including DYN peptides, neuroanatomy of the DYNs/KOR system, cellular signaling, and in vivo behavioral effects of… Click to show full abstract

This chapter provides a general introduction to the dynorphins (DYNs)/kappa opioid receptor (KOR) system, including DYN peptides, neuroanatomy of the DYNs/KOR system, cellular signaling, and in vivo behavioral effects of KOR activation and inhibition. It is intended to serve as a primer for the book and to provide a basic background for the chapters in the book.

Keywords: opioid receptor; system; fundamentals dynorphins; dynorphins kappa; kappa opioid

Journal Title: Handbook of experimental pharmacology
Year Published: 2021

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