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SYNTHESIS OF NITROMETHYL-, N -METHYLINDOLYL-, OR N -METHYLINDOLYLNITROMETHYL- SUBSTITUTED 1,4-BENZOTHIAZIN(DIAZIN)ONES AND 3-METHYL-1,4-BENZOXAZINONES FROM ALKYL 3-NITROACRYLATES

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The reactions of alkyl 3-nitroacrylates and ethyl 2-(1-methyl-1H-indol-3-yl)-3-nitroacrylate with о-aminothiophenol, о-aminophenol, о-phenylenediamine, and their substituted analogs were used for the preparation of  2-(nitromethyl)-2H-1,4-benzothiazin-3(4H)-one, 2-(1-methyl-1H-indol-3-yl)-2-(nitromethyl)-2H-1,4-benzothiazin-3(4H)-one, 3-methyl-2H-1,4-benzoxazin-2-ones, and 3-(1-methyl-1H-indol-3-yl)quinoxalin-2(1H)-ones that were structurally… Click to show full abstract

The reactions of alkyl 3-nitroacrylates and ethyl 2-(1-methyl-1H-indol-3-yl)-3-nitroacrylate with о-aminothiophenol, о-aminophenol, о-phenylenediamine, and their substituted analogs were used for the preparation of  2-(nitromethyl)-2H-1,4-benzothiazin-3(4H)-one, 2-(1-methyl-1H-indol-3-yl)-2-(nitromethyl)-2H-1,4-benzothiazin-3(4H)-one, 3-methyl-2H-1,4-benzoxazin-2-ones, and 3-(1-methyl-1H-indol-3-yl)quinoxalin-2(1H)-ones that were structurally characterized.

Keywords: methylindolyl methylindolylnitromethyl; ones methyl; synthesis nitromethyl; alkyl nitroacrylates; methyl indol; nitromethyl methylindolyl

Journal Title: Chemistry of Heterocyclic Compounds
Year Published: 2018

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