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SYNTHESIS OF N -SUBSTITUTED TETRAPROPARGYLAMINES BY CATALYTIC AMINOMETHYLATION OF Α,Ω-DIACETYLENES

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A catalytic method was developed for the synthesis of N-substituted tetrapropargylamines by reactions of α,ω-diacetylenes with 1,5,3-dioxazepanes, aldehydes (benzaldehydes, formaldehyde), and cyclic secondary amines. Click to show full abstract

A catalytic method was developed for the synthesis of N-substituted tetrapropargylamines by reactions of α,ω-diacetylenes with 1,5,3-dioxazepanes, aldehydes (benzaldehydes, formaldehyde), and cyclic secondary amines.

Keywords: synthesis substituted; aminomethylation diacetylenes; catalytic aminomethylation; tetrapropargylamines catalytic; substituted tetrapropargylamines

Journal Title: Chemistry of Heterocyclic Compounds
Year Published: 2019

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