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A multicomponent reaction of arylglyoxal hydrates, acetylacetone or acetoacetic ester, aniline or its 3(4)-substituted analogs in 1:1:2 ratio occurred upon stirring in methanol, giving 4-arylamino-5-hydroxypyrroline derivatives containing 4,5-dihydroxypyrrolines as impurities. Click to show full abstract
A multicomponent reaction of arylglyoxal hydrates, acetylacetone or acetoacetic ester, aniline or its 3(4)-substituted analogs in 1:1:2 ratio occurred upon stirring in methanol, giving 4-arylamino-5-hydroxypyrroline derivatives containing 4,5-dihydroxypyrrolines as impurities.
Keywords:
diastereoselective synthesis;
synthesis functionalized;
functionalized dihydropyrroles;
dihydropyrroles reactions;
one pot;
pot diastereoselective
Journal Title: Chemistry of Heterocyclic Compounds
Year Published: 2019
Link to full text (if available)
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Journal Title: Chemistry of Heterocyclic Compounds
Year Published: 2019
Link to full text (if available)
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recommendations!