A convenient method for the preparation of 2-(2-amino-6-oxo-1,4,5,6-tetrahydropyrimidin-5-yl)acetanilides based on the reaction of N-arylitaconimides with various carboximidamides has been proposed. In the course of the transformation, a cascade reaction occurs… Click to show full abstract
A convenient method for the preparation of 2-(2-amino-6-oxo-1,4,5,6-tetrahydropyrimidin-5-yl)acetanilides based on the reaction of N-arylitaconimides with various carboximidamides has been proposed. In the course of the transformation, a cascade reaction occurs encompassing the aza-Michael addition of carboximidamides to N -arylitaconimides and the subsequent recyclization of intermediates to dihydropyrimidine acetanilides.
Keywords:
amino oxo;
oxo tetrahydropyrimidin;
method;
tetrahydropyrimidin acetanilides
Journal Title: Chemistry of Heterocyclic Compounds
Year Published: 2021
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Journal Title: Chemistry of Heterocyclic Compounds
Year Published: 2021
Link to full text (if available)
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recommendations!