Electrophysiology is the standard method for characterizing ion channel function. Two-electrode voltage clamp is a robust and relatively simple version which can be applied to the characterization of glutamate-gated chloride… Click to show full abstract
Electrophysiology is the standard method for characterizing ion channel function. Two-electrode voltage clamp is a robust and relatively simple version which can be applied to the characterization of glutamate-gated chloride channels from Schistosoma mansoni, a potential schistomicidal target. Here, the method is described in detail, with an emphasis on the investigation of S. mansoni. GluCls.
               
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