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Tissue Analysis of Lung-Targeted Delivery of siRNA and Plasmid DNA.

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Development of nucleic acid delivery systems requires the use of adequate tissue analysis methods, especially when aiming tissue-targeted drug delivery. In this chapter, a protocol is presented for analyzing a… Click to show full abstract

Development of nucleic acid delivery systems requires the use of adequate tissue analysis methods, especially when aiming tissue-targeted drug delivery. In this chapter, a protocol is presented for analyzing a reporter signal from the lung tissue. Because lung is an important target tissue from the clinical point of view, yet represents a challenge from the histological point of view, this protocol can be used in any lung-targeting drug delivery project.

Keywords: analysis lung; delivery; tissue analysis; tissue

Journal Title: Methods in molecular biology
Year Published: 2022

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