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Peptides mediate up to 40 % of protein-protein interactions in a variety of cellular processes and are also attractive drug candidates. Thus, predicting peptide binding sites on the given protein… Click to show full abstract
Peptides mediate up to 40 % of protein-protein interactions in a variety of cellular processes and are also attractive drug candidates. Thus, predicting peptide binding sites on the given protein structure is of great importance for mechanistic investigation of protein-peptide interactions and peptide therapeutics development. In this chapter, we describe the usage of our web server, referred to as ACCLUSTER, for peptide binding site prediction for a given protein structure. ACCLUSTER is freely available for users without registration at http://zougrouptoolkit.missouri.edu/accluster .
Journal Title: Methods in molecular biology
Year Published: 2017
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