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Analysis of High-Throughput RNA Bisulfite Sequencing Data.

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Methylation of the 5-cytosine (m5C) is a common but not well-understood RNA modification, which can be detected by sequencing of bisulfite-treated transcripts (RNA-BSseq). In this Chapter, we discuss computational RNA-BSseq… Click to show full abstract

Methylation of the 5-cytosine (m5C) is a common but not well-understood RNA modification, which can be detected by sequencing of bisulfite-treated transcripts (RNA-BSseq). In this Chapter, we discuss computational RNA-BSseq data analysis methods for transcriptome-wide identification and quantification of m5C.

Keywords: throughput rna; analysis high; data analysis; rna bisulfite; analysis; high throughput

Journal Title: Methods in molecular biology
Year Published: 2017

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