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Magnetic nanoparticles have obtained great attention in the field of biomedicine in recent years owing to their excellent biocompatibility, unique magnetic properties, and ease of functionalization. Potential applications for functionalized… Click to show full abstract
Magnetic nanoparticles have obtained great attention in the field of biomedicine in recent years owing to their excellent biocompatibility, unique magnetic properties, and ease of functionalization. Potential applications for functionalized magnetic nanoparticles span biomedical imaging, treatment via magnetic hyperthermia, drug delivery, and biosensing. This chapter provides detailed procedures for the synthesis, PEGylation, and bioconjugation of monodispersed Fe3O4 nanoparticles, hollow Fe3O4 nanoparticles, porous hollow Fe3O4 nanoparticles, and dumbbell-like Au-Fe3O4 nanoparticles. We hope this article can help readers design and reproducibly prepare high-quality magnetic nanoparticles with their specific goals in mind.
Journal Title: Methods in molecular biology
Year Published: 2017
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