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Rational and Semirational Protein Design.

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This mini review gives an overview over different design approaches and methodologies applied in rational and semirational enzyme engineering. The underlying principles for engineering novel activities, enantioselectivity, substrate specificity, stability,… Click to show full abstract

This mini review gives an overview over different design approaches and methodologies applied in rational and semirational enzyme engineering. The underlying principles for engineering novel activities, enantioselectivity, substrate specificity, stability, and pH optimum are summarized.

Keywords: rational semirational; design; protein design; biology; semirational protein

Journal Title: Methods in molecular biology
Year Published: 2018

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