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Visual Acuity Testing Before and After Intravitreal Injection of rAAV2-ND4 in Patients.

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Gene therapy in ophthalmology has developed rapidly, and there has been a breakthrough in the treatment of Leber's hereditary optic neuropathy. After receiving an intravitreal injection of rAAV2-ND4, patients followed… Click to show full abstract

Gene therapy in ophthalmology has developed rapidly, and there has been a breakthrough in the treatment of Leber's hereditary optic neuropathy. After receiving an intravitreal injection of rAAV2-ND4, patients followed up over a certain time period showed a definite increase in visual acuity. Visual acuity testing is critical for assessing the efficacy of rAAV2-ND4 intravitreal injection.

Keywords: raav2 nd4; intravitreal injection; visual acuity

Journal Title: Methods in molecular biology
Year Published: 2018

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