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The Open Field Test for Measuring Locomotor Activity and Anxiety-Like Behavior.

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The open field test is used in studies of the neurobiological basis of anxiety and screening for novel drug targets and anxiolytic compounds. This test uses a camera to measure… Click to show full abstract

The open field test is used in studies of the neurobiological basis of anxiety and screening for novel drug targets and anxiolytic compounds. This test uses a camera to measure movement of the test animal in the peripheral and central zones of a 42 × 42 × 42 cm polyvinyl chloride box. This chapter describes a protocol for carrying out the open-field test for assessment of locomotion and anxiety-like behavior in mice.

Keywords: field test; anxiety like; open field; test

Journal Title: Methods in molecular biology
Year Published: 2019

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