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Integrating prior knowledge of pathway-level information can enhance power and facilitate interpretation of gene expression data analyses. Here, we provide a practical demonstration of the value of gene set or… Click to show full abstract
Integrating prior knowledge of pathway-level information can enhance power and facilitate interpretation of gene expression data analyses. Here, we provide a practical demonstration of the value of gene set or pathway enrichment testing and extend such techniques to identify and characterize transcriptional subpopulations from single-cell RNA-sequencing data using pathway and gene set overdispersion analysis (PAGODA).
Keywords:
analysis;
biology;
pathway analysis;
gene;
differential pathway
Journal Title: Methods in molecular biology
Year Published: 2019
Link to full text (if available)
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Journal Title: Methods in molecular biology
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!