LAUSR

At the present time Optical Coherence Tomography (OCT) is among the most commonly used non-invasive imaging methods for the acquisition of large volumetric scans of human retinal tissues and vasculature. Due to tissue-dependent speckle noise, the elaboration of automated segmentation models has become an important task in the field of medical image processing. We propose a novel, purely data driven geometric approach to order-constrained 3D OCT retinal cell layer segmentation which takes as input data in any metric space. This makes it unbiased and therefore amenable for the detection of local anatomical changes of retinal tissue structure. To demonstrate robustness of the proposed approach we compare four different choices of features on a data set of manually annotated 3D OCT volumes of healthy human retina. The quality of computed segmentations is compared to the state of the art in terms of mean absolute error and Dice similarity coefficient.