LAUSR

Since the introduction of neuroleptics in the treatment of psychiatric disorders in the late 1950s, drug-induced extrapyramidal syndromes have been well documented [1]. Fatal hyperpyrexia during chlorpromazine therapy was first reported in 1956 [2] and the so called “syndrome malin des neuroleptiques” or neuroleptic malignant syndrome (NMS) was fully described by French authors in 1967 [3] and 1968 [1]. Though rare, more than 200 cases have been reported since then, primarily in the French and Anglo-Saxon literature.