LAUSR

Early detection and accurate diagnosis have strong impacts on cancer care; therefore, pathological diagnosis of biopsy specimen is important. It is too late that the lesion is followed up until the carcinoma invades the submucosa or more. For the better quality of life (QOL) of patients, carcinomas should be endoscopically diagnosed and resected before metastasis. To achieve correct histological diagnosis on early-stage gastric carcinomas by biopsy specimen, it is necessary to understand the difference in histological diagnosis between Japanese and Western pathologists and learn the characteristic histological features of noninvasive well-differentiated adenocarcinomas, especially those of low-grade atypia. In addition, for selecting the suitable therapy, it is also necessary to know the clinicopathological features of special types of gastric carcinomas and how to correctly perform a histological evaluation of endoscopically resected specimens.