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Role of Mitochondria in Host-Pathogen Interaction.

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The centrality of the mitochondrion in the evolution and control of the cellare now supported by many experimental studies. Not only with regard to the energy metabolism but also and… Click to show full abstract

The centrality of the mitochondrion in the evolution and control of the cellare now supported by many experimental studies. Not only with regard to the energy metabolism but also and especially with regard to the other functions indispensable for the cell such as apoptosis and the control of innate immunity through different complex cell signaling pathways. All this makes them one of the main targets during infections supported by pathogenic microorganisms. The interaction and control of these organelles by pathogens results, from the latest experimental evidence, of fundamental importance in the fate of the host cell and in the progression of infectious diseases.

Keywords: role mitochondria; pathogen interaction; host; interaction; host pathogen; mitochondria host

Journal Title: Advances in experimental medicine and biology
Year Published: 2019

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