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Autophagy and Tumor Cell Death.

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There exists an intricate collaboration between autophagy and other types of PCD. These processes can be activated in parallel or sequentially, and have either common or opposite objectives. Determining which… Click to show full abstract

There exists an intricate collaboration between autophagy and other types of PCD. These processes can be activated in parallel or sequentially, and have either common or opposite objectives. Determining which interactions between them are important in the regulation of cell death. A comprehensive and in-depth study of the crosstalk between autophagy and apoptosis, necroptosis, or pyroptosis will bring breakthroughs in the treatment of many diseases, including cancer, cardiovascular disease, and neurodegenerative disorders.

Keywords: tumor cell; cell; autophagy tumor; cell death

Journal Title: Advances in experimental medicine and biology
Year Published: 2020

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