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Introduction to the multi-author-review: emerging advances in the structural chemistry of DNA strand break repair

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DNA strand breaks present a complex challenge for our cells, and the integrity of the DNA damage response machinery is critical for preventing cancer, premature aging, and neurodegenerative syndromes amongst… Click to show full abstract

DNA strand breaks present a complex challenge for our cells, and the integrity of the DNA damage response machinery is critical for preventing cancer, premature aging, and neurodegenerative syndromes amongst other ailments. This multi-author review issue presents emerging topics relevant to understanding the fundamental structural mechanisms of DNA strand break sensing, signaling, and repair.

Keywords: chemistry; multi author; author review; strand break; dna strand

Journal Title: Cellular and Molecular Life Sciences
Year Published: 2019

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